Preventive health powered by microRNA intelligence

See change sooner. Extend healthspan.

miRoncol is building a microRNA intelligence platform to make preventive health earlier, more personal and more informed. It begins with miCheckup, its multi-cancer early detection test, and is designed to learn over time across four major chronic disease domains: cancer, cardiovascular, neurodegenerative and metabolic disease.

Published foundation Oncology miCheckup · early cancer detection
Detection research Cardiovascular Heart and vascular disease
Detection research Neurodegenerative Neurological decline
Detection research Metabolic Metabolic dysfunction
One microRNA intelligence platformFour major chronic disease domains
01 · The platform

MicroRNA intelligence

Read a regulatory control layer that sits upstream of many traditional biomarkers and connects research across multiple disease domains.

See how it works
02 · First focused application

miCheckup

An Early Cancer Detection Test grounded in the first peer-reviewed publication of a miRNA-based multi-cancer early detection model.

See the miCheckup Cancer Test
03 · The longitudinal advantage

Health over time

Begin while healthy, establish a personal molecular history and add context to change, intervention and response.

Understand the history
Why prevention starts early

You cannot recreate a healthy baseline later.

Capturing a molecular profile while a person feels well creates a reference for recognizing future change. If that history does not yet exist, a single sample can still be analyzed for a disease-associated pattern present now.

Current-state intelligence What molecular pattern is present today?
Longitudinal intelligence How has that pattern changed from personal health?
“A single test captures the moment. Longitudinal intelligence helps us understand the change.”
Victoria Xu
Victoria Xu Co-Founder & Chief Executive Officer, miRoncol Health
The Nobel Prize · 60-second explainer

The foundational science behind the platform.

The 2024 Nobel Prize in Physiology or Medicine recognized the discovery of microRNA and its role in post-transcriptional gene regulation. This independent video explains the biological control layer miRoncol is learning to read.

Explore the deeper science Independent scientific education from the Nobel Prize. The Nobel Prize does not endorse miRoncol or its products.
A published research foundation

Peer-reviewed science. A focused first application.

miRoncol’s platform direction begins with published research in blood-based microRNA patterns for multi-cancer detection. miCheckup translates that foundation into the company’s first focused application.

Cancers2022

Detection of twelve common cancers using serum microRNA expression profiles

Peer-reviewed research investigating serum microRNA signatures across twelve cancer types.

Read the paper
Scientific Reports2024

Noninvasive multi-cancer detection using blood-based cell-free microRNAs

A peer-reviewed study examining whether microRNA patterns in blood could distinguish multiple cancers from non-cancer samples.

Read the paper
First focused applicationmiCheckup

An Early Cancer Detection Test grounded in the first peer-reviewed publication of a miRNA-based multi-cancer early detection model.

miCheckup is miRoncol’s first focused application, informed by studies published in Scientific Reports and Cancers.

Visit the miCheckup Cancer Test
A branching platform

One intelligence platform. Four major chronic disease domains.

miRoncol is focusing its research on four major chronic disease domains that shape healthspan: cancer, cardiovascular disease, neurodegenerative disease and metabolic disease. The evidence, research questions and stage of development differ by application.

miR

Shared intelligence core

Broad microRNA measurement, AI-assisted pattern recognition and longitudinal context.

Research direction

Cardiovascular

Regulatory patterns connected to vascular biology, cardiac stress and inflammation.

Research direction

Neurodegenerative

Patterns under investigation in neurological decline and neuroinflammatory biology.

Research direction

Metabolic

Regulatory pathways connected to insulin response, energy balance and metabolic dysfunction.

Scientific discipline matters: these directions are not presented as equally validated products. Each moves forward only as the evidence supports it.

A platform designed to keep learning

Capture broadly today. See more tomorrow.

Beginning with comprehensive sequencing preserves the ability to ask new questions of earlier measurements as research and analytical models advance.

NGS · Preserve

Capture the whole measured panel.

Build a broad molecular record that extends beyond the signals we know to look for today.

AI + analytics · Revisit

Return with better vision.

Apply evolving pattern-recognition models to investigate when a newly understood signal emerged and how it changed.

Targeted PCR · Focus

Measure a known signature.

Translate selected signatures into more focused assays for specific research and future applications.

Christopher M. Gallagher, MD
“NGS preserves the possibilities. PCR provides the focus. Longitudinal data creates the history.”
Christopher M. Gallagher, MD Co-Founder & Chief Medical Officer · Medical Oncologist
Why miRoncol

A team built to move from molecular research to preventive health.

Scientific, medical and company leadership working together around one question: what becomes possible when health is measured earlier and understood over time?

Our vision

Make earlier prevention against the diseases that shorten healthspan accessible to everyone.

We envision a future where people can recognize meaningful biological change before symptoms appear and act earlier to protect more healthy years.

Our mission

Build microRNA intelligence for preventive health.

Use convenient biological samples, AI-assisted pattern recognition and longitudinal data to recognize meaningful change earlier. Translate validated signals into focused tests.

Victoria Xu
Victoria Xu Co-Founder & Chief Executive Officer

Entrepreneur and investor with graduate training in bioinformatics and public management, leading the platform from research toward preventive-health applications.

Christopher M. Gallagher, MD
Christopher M. Gallagher, MD Co-Founder & Chief Medical Officer

Practicing medical oncologist with more than 20 years in cancer care and clinical research, guiding clinical strategy and scientific rigor.

Gilles Erb, PhD
Gilles Erb, PhD Medical & Scientific Director

Former Global Scientific Director for Integrated Molecular Medicine at Roche (FMI), with more than 20 years in oncology diagnostics and clinical validation.

Hai Hu, PhD
Hai Hu, PhD Co-Founder & Chief Scientific Officer

Award-winning bioinformatics scientist behind miRoncol’s peer-reviewed blood-based microRNA models for multi-cancer early detection.

Follow the work as it develops.

Company milestones, research progress, partnerships and perspectives from the miRoncol team.

Request company updates

Start earlier. Understand change. Protect more healthy years.

Explore the deeper microRNA intelligence platform story or visit the miCheckup early cancer detection test.