MicroRNA intelligence
Read a regulatory control layer that sits upstream of many traditional biomarkers and connects research across multiple disease domains.
See how it worksmiRoncol is building a microRNA intelligence platform to make preventive health earlier, more personal and more informed. It begins with miCheckup, its multi-cancer early detection test, and is designed to learn over time across four major chronic disease domains: cancer, cardiovascular, neurodegenerative and metabolic disease.
Read a regulatory control layer that sits upstream of many traditional biomarkers and connects research across multiple disease domains.
See how it works
An Early Cancer Detection Test grounded in the first peer-reviewed publication of a miRNA-based multi-cancer early detection model.
See the miCheckup Cancer TestBegin while healthy, establish a personal molecular history and add context to change, intervention and response.
Understand the historyCapturing a molecular profile while a person feels well creates a reference for recognizing future change. If that history does not yet exist, a single sample can still be analyzed for a disease-associated pattern present now.
“A single test captures the moment. Longitudinal intelligence helps us understand the change.”
The 2024 Nobel Prize in Physiology or Medicine recognized the discovery of microRNA and its role in post-transcriptional gene regulation. This independent video explains the biological control layer miRoncol is learning to read.
Explore the deeper science Independent scientific education from the Nobel Prize. The Nobel Prize does not endorse miRoncol or its products.miRoncol’s platform direction begins with published research in blood-based microRNA patterns for multi-cancer detection. miCheckup translates that foundation into the company’s first focused application.
Peer-reviewed research investigating serum microRNA signatures across twelve cancer types.
Read the paperA peer-reviewed study examining whether microRNA patterns in blood could distinguish multiple cancers from non-cancer samples.
Read the paper
miCheckup is miRoncol’s first focused application, informed by studies published in Scientific Reports and Cancers.
Visit the miCheckup Cancer TestmiRoncol is focusing its research on four major chronic disease domains that shape healthspan: cancer, cardiovascular disease, neurodegenerative disease and metabolic disease. The evidence, research questions and stage of development differ by application.
Broad microRNA measurement, AI-assisted pattern recognition and longitudinal context.
The research foundation behind miRoncol’s multi-cancer early detection test, miCheckup.
See the miCheckup Early Cancer Detection TestRegulatory patterns connected to vascular biology, cardiac stress and inflammation.
Patterns under investigation in neurological decline and neuroinflammatory biology.
Regulatory pathways connected to insulin response, energy balance and metabolic dysfunction.
Scientific discipline matters: these directions are not presented as equally validated products. Each moves forward only as the evidence supports it.
Beginning with comprehensive sequencing preserves the ability to ask new questions of earlier measurements as research and analytical models advance.
Build a broad molecular record that extends beyond the signals we know to look for today.
Apply evolving pattern-recognition models to investigate when a newly understood signal emerged and how it changed.
Translate selected signatures into more focused assays for specific research and future applications.
“NGS preserves the possibilities. PCR provides the focus. Longitudinal data creates the history.”Christopher M. Gallagher, MD Co-Founder & Chief Medical Officer · Medical Oncologist
Scientific, medical and company leadership working together around one question: what becomes possible when health is measured earlier and understood over time?
We envision a future where people can recognize meaningful biological change before symptoms appear and act earlier to protect more healthy years.
Use convenient biological samples, AI-assisted pattern recognition and longitudinal data to recognize meaningful change earlier. Translate validated signals into focused tests.
Entrepreneur and investor with graduate training in bioinformatics and public management, leading the platform from research toward preventive-health applications.
Practicing medical oncologist with more than 20 years in cancer care and clinical research, guiding clinical strategy and scientific rigor.
Former Global Scientific Director for Integrated Molecular Medicine at Roche (FMI), with more than 20 years in oncology diagnostics and clinical validation.
Award-winning bioinformatics scientist behind miRoncol’s peer-reviewed blood-based microRNA models for multi-cancer early detection.
Company milestones, research progress, partnerships and perspectives from the miRoncol team.
Explore the deeper microRNA intelligence platform story or visit the miCheckup early cancer detection test.
Tell us where you are and which area interests you. If a relevant research opportunity develops, the miRoncol team may contact you with more information.